Compounds > 1-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxo-1-phenylethyl]-4-piperidinecarboxylic acid ethyl ester

Page last updated: 2024-07-31 23:16:03

1-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxo-1-phenylethyl]-4-piperidinecarboxylic acid ethyl ester

Description

1-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxo-1-phenylethyl]-4-piperidinecarboxylic acid ethyl ester : no description available [CHeBI]

Cross-References

ID Source	ID
PubMed CID	3240212
CHEMBL ID	1578060
CHEBI ID	114525

Synonyms (11)

Synonym
ethyl 1-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxo-1-phenylethyl]piperidine-4-carboxylate
MLS000086414
smr000021916
CHEBI:114525
AKOS001777815
HMS2324F12
CHEMBL1578060
1-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxo-1-phenylethyl]-4-piperidinecarboxylic acid ethyl ester
Q27195928
SR-01000548618-1
sr-01000548618

Drug Classes (1)

Class	Description
amino acid amide	An amide of an amino acid formed formally by conversion of the carboxy group to a carboxamido group.

Protein Targets (4)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)
glp-1 receptor, partial	Homo sapiens (human)	Potency	10.0000	AID624417
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	25.1189	AID1030
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	12.5893	AID926; AID938
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	89.1251	AID504333

Bioassays (7)

Assay ID	Title	Year	Journal	Article
AID1745845	Primary qHTS for Inhibitors of ATXN expression	2022	The Journal of biological chemistry, 08, Volume: 298, Issue:8 ISSN: 1083-351X
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression	2022	The Journal of biological chemistry, 08, Volume: 298, Issue:8 ISSN: 1083-351X
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7 ISSN: 1945-7170	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7 ISSN: 1945-7170	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 ISSN: 1552-4922	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1 ISSN: 1557-8127	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	3 (60.00)	24.3611
2020's	1 (20.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%

Substance	Classes	Roles	Relationship Strength
midodrine	amino acid amide; aromatic ether; secondary alcohol	alpha-adrenergic agonist; prodrug; sympathomimetic agent; vasoconstrictor agent	low
oxethazaine	amino acid amide		low
prilocaine	amino acid amide; monocarboxylic acid amide	anticonvulsant; local anaesthetic	low
qx-222	amino acid amide		low
ambucetamide	amino acid amide		low
trimecaine	amino acid amide		low
[2-(2,6-dimethylanilino)-2-oxoethyl]-diethyl-(phenylmethyl)ammonium	amino acid amide		low
Phenylacetylglycine dimethylamide	amino acid amide		low
pyrrocaine	amino acid amide		low
monoethylglycinexylidide	amino acid amide	drug metabolite	low
etidocaine	amino acid amide	local anaesthetic	low
lidofenin	amino acid amide		low
mebrofenin	amino acid amide		low
glycine amide	amino acid amide; glycine derivative		low
calpeptin	amino acid amide		low
glycinexylidide	amino acid amide	drug metabolite	low
N1-(4-nitrophenyl)-2-amino-3-(benzylthio)propanamide	amino acid amide		low
leucine-beta-naphthylamide	amino acid amide; L-leucine derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
phenylalanine-beta-naphthylamide	amino acid amide; L-phenylalanine derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
prolinamide	amino acid amide; L-proline derivative; pyrrolidinecarboxamide		low
2',6'-pipecoloxylidide	amino acid amide		low
safinamide	amino acid amide		low
tyrosinamide	amino acid amide; L-tyrosine derivative		low
arginine beta-naphthylamide	amino acid amide; L-arginine derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
3-hydroxylidocaine	amino acid amide		low
isoglutamine	amino acid amide; glutamic acid derivative		low
gamma-glutamyl-2-naphthylamide	amino acid amide; L-glutamic acid derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
2-[carboxymethyl-[2-(2,6-diethylanilino)-2-oxoethyl]amino]acetic acid	amino acid amide		low
beta-alanine amide	amino acid amide		low
ns 105	amino acid amide		low
bortezomib	amino acid amide; L-phenylalanine derivative; pyrazines	antineoplastic agent; antiprotozoal drug; protease inhibitor; proteasome inhibitor	low
tryptophanamide	amino acid amide; tryptophan derivative	human metabolite	low
phenylalanine amide	amino acid amide; phenylalanine derivative		low
argininamide	amino acid amide; guanidines; L-arginine derivative		low
a 80987	amino acid amide		low
2-(1,3-benzodioxol-5-ylamino)-N-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetamide	amino acid amide		low
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-(4-morpholinyl)acetamide	amino acid amide		low
N-(1,3-benzodioxol-5-yl)-2-[4-(4-phenyl-2-thiazolyl)-1-piperazinyl]acetamide	amino acid amide		low
3-fluoro-N-[1-[2-[(2-fluorophenyl)methylamino]-2-oxoethyl]-4-piperidinyl]benzamide	amino acid amide		low
N-[2-(1H-benzimidazol-2-yl)ethyl]-2-[4-(5-fluoro-1-benzotriazolyl)-1-piperidinyl]acetamide	amino acid amide		low
3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl ester	amino acid amide		low
2-(butan-2-ylamino)-N-[4-[5-[[2-(butan-2-ylamino)-1-oxoethyl]amino]-1,3-benzoxazol-2-yl]phenyl]acetamide	amino acid amide		low
N-[5-[[2-(4-methylanilino)-2-oxoethyl]thio]-1,3,4-thiadiazol-2-yl]-2-(4-morpholinyl)acetamide	amino acid amide		low
2-(butylamino)-N-[4-[5-[[2-(butylamino)-1-oxoethyl]amino]-1,3-benzoxazol-2-yl]phenyl]acetamide	amino acid amide		low
5-bromo-3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl ester	amino acid amide		low
3-[(3aR,6aS)-6'-chloro-5-(4-chlorophenyl)-7'-methyl-2',4,6-trioxo-1-spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]yl]propanamide	amino acid amide		low
2-(cyclohexylamino)-N-(4-ethylphenyl)-2-sulfanylideneacetamide	amino acid amide		low
L-histidine 2-naphthylamide	amino acid amide; L-histidine derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
2-anilino-N-(4-fluorophenyl)acetamide	amino acid amide		low
N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide	amino acid amide; glycine derivative		low
2-(4-methyl-1-piperazinyl)-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide	amino acid amide		low
N-(4-fluorophenyl)-2-[4-[oxo(1-piperidinyl)methyl]-1-piperazinyl]acetamide	amino acid amide		low
N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(4-tert-butylphenyl)sulfonylamino]acetamide	amino acid amide		low
2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid methyl ester	amino acid amide		low
4-(5-methyl-2-furanyl)-2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-3-thiophenecarboxylic acid ethyl ester	amino acid amide		low
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]acetamide	amino acid amide		low
N'-(4-phenyl-2-thiazolyl)-N-(2-pyridinylmethyl)oxamide	amino acid amide		low
N'-[(4-chlorophenyl)methyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]oxamide	amino acid amide		low
N-(3-chlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide	amino acid amide		low
3-methyl-5-[[1-oxo-2-(2-pyridinylmethylamino)ethyl]amino]thiophene-2,4-dicarboxylic acid diethyl ester	amino acid amide		low
2-[2-(difluoromethoxy)anilino]-1-(2,3-dihydroindol-1-yl)ethanone	amino acid amide		low
2-(1-azepanyl)-N-[4-(dimethylsulfamoyl)phenyl]acetamide	amino acid amide		low
2-(2,3-dimethylanilino)-N-(2,3-dimethylphenyl)acetamide	amino acid amide		low
N-(3-cyano-2-thiophenyl)-2-[4-(2,5-dimethylphenyl)sulfonyl-1-piperazinyl]acetamide	amino acid amide		low
2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methyl-methylamino]-N-(2-ethylphenyl)acetamide	amino acid amide		low
2-(4-methyl-1-piperidinyl)-N-[2-(phenylthio)phenyl]acetamide	amino acid amide		low
N-(2-bromophenyl)-2-[[2-(2,6-dimethylanilino)-2-oxoethyl]-methylamino]acetamide	amino acid amide		low
N-(4-cyano-1-phenyl-1H-pyrazol-5-yl)-2-(4-methylpiperazino)acetamide	amino acid amide		low
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamide	amino acid amide		low
N'-[4-(1-adamantyl)-2-thiazolyl]-N-[(4-fluorophenyl)methyl]oxamide	amino acid amide		low
N-(3-chloro-4-methylphenyl)-2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)acetamide	amino acid amide		low
N-(4-nitrophenyl)-2-(1-pyrrolidinyl)acetamide	amino acid amide		low
2-(benzenesulfonamido)-N-[(2-methoxyphenyl)methyl]propanamide	amino acid amide		low
N-cycloheptyl-2-(cyclohexylamino)-2-sulfanylideneacetamide	amino acid amide		low
6-methyl-2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester	amino acid amide		low
N'-[4-(dimethylamino)phenyl]-N-propyloxamide	amino acid amide		low
N-tert-butyl-2-[[(3-nitrophenyl)-oxomethyl]hydrazo]-2-oxoacetamide	amino acid amide		low
2-[[2-(4-chlorophenoxy)-1-oxoethyl]hydrazo]-N-(2-methoxy-5-methylphenyl)-2-oxoacetamide	amino acid amide		low
2-[[2-(2,4-dichlorophenoxy)-1-oxopropyl]hydrazo]-N-(4-methoxyphenyl)-2-oxoacetamide	amino acid amide		low
2-[[2-furanyl(oxo)methyl]hydrazo]-N-(2-methoxy-5-methylphenyl)-2-oxoacetamide	amino acid amide		low
N-(3-fluorophenyl)-2-oxo-4,10-dihydro-3H-pyrimido[1,2-a]benzimidazole-4-carboxamide	amino acid amide		low
N-[2-(cyclopentylamino)-2-oxoethyl]-4,7-dimethyl-N-(2-methylphenyl)-2-oxo-3H-pyrido[1,2-a]pyrimidine-4-carboxamide	amino acid amide		low
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-(4-morpholinyl)acetamide	amino acid amide		low
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-(1-phenylethyl)acetamide	amino acid amide		low
N-[2-(2-ethyl-1-piperidinyl)ethyl]-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]acetamide	amino acid amide		low
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(3-methyl-1-piperidinyl)-2-phenylacetamide	amino acid amide		low
N-(1,3-benzodioxol-5-yl)-2-[4-(4-chlorophenyl)sulfonyl-1-piperazinyl]acetamide	amino acid amide		low
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-(3-pyridinylmethyl)acetamide	amino acid amide		low
2-[4-[2-(3,5-dimethoxyanilino)-2-oxoethyl]-1-piperazinyl]-N-(4-ethoxyphenyl)acetamide	amino acid amide		low
N-(4-methoxyphenyl)-2-(N-methylanilino)-2-(6-nitro-1,3-benzodioxol-5-yl)acetamide	amino acid amide		low
2-[[2-[(2,5-dimethylphenyl)sulfonylamino]-1-oxoethyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	amino acid amide		low
N-decyl-N'-(2-pyridinyl)oxamide	amino acid amide		low
3-(3-bromoanilino)-2-oxo-1H-indole-3-carbonitrile	amino acid amide		low
N-(1,3-benzothiazol-2-yl)-2-ethylsulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide	amino acid amide		low
N-cyclopentyl-2-(2,3-dihydroindol-1-yl)-2-(4-methoxyphenyl)acetamide	amino acid amide		low
2-(3-oxo-2,4-dihydroquinoxalin-1-yl)-2-phenyl-N-(4-propan-2-ylphenyl)acetamide	amino acid amide		low
N-[4-chloro-3-(dimethylsulfamoyl)phenyl]-2-[(phenylmethyl)amino]acetamide	amino acid amide		low
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-2-(2-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide	amino acid amide		low
2-anilino-N-(4-methylphenyl)-2-phenylacetamide	amino acid amide		low
2-anilino-N-(3,5-dimethylphenyl)-2-phenylacetamide	amino acid amide		low
N-(3-chloro-2-methylphenyl)-2-[3-(dimethylsulfamoyl)anilino]acetamide	amino acid amide		low
2-(5-chloro-2,4-dimethoxyanilino)-1-(4-ethyl-1-piperazinyl)-1-propanone	amino acid amide		low
2-(2-chloro-4-methylanilino)-N-[3-(dimethylsulfamoyl)phenyl]acetamide	amino acid amide		low
N-(2,5-difluorophenyl)-2-(1-pyrrolidinyl)acetamide	amino acid amide		low
N-(2-bromophenyl)-2-[5-(dimethylsulfamoyl)-2-(ethylamino)anilino]acetamide	amino acid amide		low
N-(3-chloro-4-fluorophenyl)-2-[5-(dimethylsulfamoyl)-2-(ethylamino)anilino]acetamide	amino acid amide		low
N-(4-bromo-2-fluorophenyl)-2-(2,4-dimethoxyanilino)acetamide	amino acid amide		low
LSM-24595	amino acid amide		low
5-carbamoyl-4-methyl-2-[[1-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]amino]-3-thiophenecarboxylic acid ethyl ester	amino acid amide		low
N-[(4-chlorophenyl)methyl]-2-[[[(2-fluorophenyl)methyl-(phenylmethyl)amino]-sulfanylidenemethyl]amino]acetamide	amino acid amide		low
N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-piperidinyl)-2-phenylacetamide	amino acid amide		low
N-[2-chloro-5-[ethyl(phenyl)sulfamoyl]phenyl]-2-[methyl-(1-methyl-4-piperidinyl)amino]acetamide	amino acid amide		low
3,4-dihydro-1H-isoquinolin-2-yl-[1-(8-quinolinylsulfonyl)-2-pyrrolidinyl]methanone	amino acid amide		low
1-(4-tert-butylphenyl)sulfonyl-N-(2-pyridinylmethyl)-2-piperidinecarboxamide	amino acid amide		low
(3S,3'aR,8'aS,8'bS)-5-ethyl-2'-(phenylmethyl)spiro[1H-indole-3,4'-3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine]-1',2,3'-trione	amino acid amide		low
cefatrizine	amino acid amide; carboxylic acid; cephalosporin; phenols; semisynthetic derivative; triazoles	antibacterial drug; EC 2.7.11.20 (elongation factor 2 kinase) inhibitor	low
N-(1,3-benzothiazol-2-yl)-2-(2,6-dimethyl-4-morpholinyl)acetamide	amino acid amide		low
N-(3,4-dichlorophenyl)-2-[4-(1-piperidinylsulfonyl)-1-piperazinyl]acetamide	amino acid amide		low
iprovalicarb	amino acid amide; carbamate ester; valine derivative		low
vildagliptin	amino acid amide		low
(3aR,4S,9aR,9bS)-N,2-bis(4-chlorophenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazine-4-carboxamide	amino acid amide		low
eluxadoline	amino acid amide; benzamides; imidazoles; L-phenylalanine derivative; methoxybenzoic acid	delta-opioid receptor antagonist; gastrointestinal drug; kappa-opioid receptor agonist; mu-opioid receptor agonist	low
gosogliptin	amino acid amide		low
teneligliptin	amino acid amide		low
Glycyl-H-1152	amino acid amide		low
2-[(5-bromo-2-thiophenyl)sulfonylamino]-N-cyclopentyl-2-phenylacetamide	amino acid amide		low
N-[2-(3,4-dimethoxyphenyl)ethyl]-N'-(12-oxo-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-2-yl)oxamide	amino acid amide		low
2-[1-[(2-chloro-6-fluorophenyl)methyl]-3-oxo-2-piperazinyl]-N-prop-2-enylacetamide	amino acid amide		low
aspartic acid beta-naphthylamide	amino acid amide; L-aspartic acid derivative; N-(2-naphthyl)carboxamide	chromogenic compound	low
(3aR,4S,9aR,9bS)-N-(4-chlorophenyl)-2-(4-fluorophenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazine-4-carboxamide	amino acid amide		low
N-[[3-(4-nitrophenyl)sulfonyl-2-oxazolidinyl]methyl]-N'-(2-pyridinylmethyl)oxamide	amino acid amide		low
Majusculamide AB	amino acid amide	metabolite	low
anagliptin	amino acid amide		low
1-(4-methyl-1-piperazinyl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethanone	amino acid amide		low
bactobolin	amino acid amide		low
N-(1,3-benzodioxol-5-yl)-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamide	amino acid amide		low
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-[2-(methylthio)phenyl]acetamide	amino acid amide		low
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-(3-fluorophenyl)acetamide	amino acid amide		low
N-[2-(4-chlorophenyl)ethyl]-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamide	amino acid amide		low

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Inflammation	0	1	2010	2010	14.0	high	0	0	0	1	0	0
Innate Inflammatory Response	0	1	2010	2010	14.0	high	0	0	0	1	0	0